Popular guidelines

What does it mean if my MCH is high?

What does it mean if my MCH is high?

High MCH scores are commonly a sign of macrocytic anemia. This condition occurs when the blood cells are too big, which can be a result of not having enough vitamin B12 or folic acid in the body.

What is Macrocytosis a symptom of?

Usually, macrocytosis is caused by nutritional deficiency, specifically of folate or vitamin B12. This can arise from a hereditary condition called pernicious anemia, in which a protein called intrinsic factor is lacking in your gut. Intrinsic factor helps your body absorb vitamin B12.

What drugs can cause Macrocytosis?

Common drugs that cause macrocytosis are hydroxyurea, methotrexate, zidovudine, azathioprine, antiretroviral agents, valproic acid, and phenytoin (Table 1).

How common is Macrocytosis?

Background: Macrocytosis is a relatively common finding in adult patients undergoing automated complete blood cell (CBC) counting with an incidence varying from 1.7 % to 3.6 %. Approximately 60% will not have associated anemia.